Toxicology of the immune system

a human approach
  • 322 Pages
  • 0.20 MB
  • English
Van Nostrand Reinhold , New York, London
StatementRobert Burrell, Dennis K. Flaherty, Leonard J. Sauers.
ContributionsFlaherty, Dennis K., Sauers, Leonard J.
The Physical Object
Pagination322p. :
ID Numbers
Open LibraryOL21422733M
ISBN 100442008368

Toxicology of the Immune System: A Human Approach: Medicine & Health Science Books @ Toxicology of the immune system book. This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology.

Description. Comprehensive Toxicology, Third Edition, discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects.

Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system. Recognition by regulatory agencies that the immune system is an important, as well as sensitive, target organ for chemical- and drug-induced toxicity is another indication of the growth of this subdiscipline of toxicology.

This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies.

Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume. The immune system comprises numerous lymphoid organs and different cellular populations with a variety of functions.

The bone marrow and the thymus support the production of mature T and B lymphocytes and myeloid cells, such as macrophages and polymorphonuclear cells (PMN), and are referred to as primary lymphoid organs. Within each of these five major sections are several carefully selected topics that reflect the current state of human toxicology.

From tissue uptake of mercury to the effects of drugs on immune systems, the text provides much-needed information quickly and easily. An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple” molecular systems, to complex human communities, with expertise from a spectrum of interacting rs are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are.

The book succeeds both in discussing the basic principles of the immune system, and then how these principles play out in myriad diseases and conditions. William Clark introduces and defines medical terms, but he is smart not to get bogged down in them - the book is aimed at understanding, not jargon/5(22).

Immunotoxicology, the science of poisons to the immune system, is devoted to the study of adverse effects of pharmaceuticals and all other chemicals on the immune responsiveness of treated or exposed living hosts (immunosuppression and immunostimulation) as well as the induction of hypersensitivity and autoimmunity.

Although immunotoxicology is an active area of toxicology, this is still a. Toxicology describes the adverse and, in the worst case, lethal effects of substances on tissues, organs, organisms, and even on systems of higher complexity.

However, these effects are the outcome of damage to single cells, which results in loss of the cell's specific function for a particular tissue, organ, and system. Toxic responses might arise when the immune system either (1) acts as a passive target of chemical insult, leading to a relatively broad-spectrum loss or potentiation of function; or (2) responds to the antigenic specificity of the chemical as part of a specific immune by: Get this from a library.

Comprehensive toxicology. 5: Toxicology of the immune system. [I Glenn Sipes; Charlene A ¿MacQueen-McQueen; A Jay Gandolfi]. Book Description. The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia.

Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Introduction --Basic immunology --Basic principles of toxicology --Effector mechanisms: immunopharmacology --Effector mechanisms: expression of immunity --Mechanisms of injury by the immune system --Damage to the immune system --Intentional modulation of the immune response: immunopotentiation and immunosuppression --Assessment of secondary immunodeficiencies in man and animals --Relevance of immunotoxicologic findings to human immune.

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When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general.

You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution. Book Description.

Reflecting the broad and interdisciplinary nature of toxicology, this third edition of Principles of Toxicology explores the biochemical, physiological, and environmental aspects of the subject. This new edition is updated and revised to include reference to several major new directions in the science of toxicology, including significant changes in thinking about cancer and.

Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative.

Popular Toxicology Books Showing of 60 The Poisoner's Handbook: Murder and the Birth of Forensic Medicine in Jazz Age New York (Hardcover) by. Deborah Blum (shelved 10 times as toxicology) avg rating — 27, ratings — published Want to Read saving Want to Read Missing: immune system.

Immunotoxicity: Toxic Effects on the Immune System Stephen M. Roberts Center for Environmental and Human Toxicology, University of Florida, Gainesville, Florida, USACited by: 1. Editor of three books and author of manuscripts, she appears on Thomson Reuters’s list of the top 1% most highly cited researchers in pharmacology and toxicology.

Montiero-Riviere serves on national and international expert review panels as well as having editorial duties for eight journals. Toxicology is a field of science that helps us understand the harmful effects that chemicals, substances, or situations, can have on people, animals, and the environment.

Some refer to toxicology as the “Science of Safety” because as a field it has evolved from a science focused on studying poisons and adverse effects of chemical exposures, to a science devoted to studying safety.

Description Toxicology of the immune system EPUB

Click to launch & play an online audio visual presentation by Dr. Leigh Ann Burns Naas on Toxicology of the immune system, part of a collection of online lectures. In addition to his rich publication history—which includes approximately hypothesis-driven peer-reviewed papers and 25 reviews or book chapters—Dr.

Kaminski co-authored the chapter on “Toxic Responses of the Immune System” in the seventh, eighth, and ninth editions of Casarett and Doull’s Toxicology: The Basic Science of Poisons. Home Books Casarett and Doull's Toxicology: Indeed, in some instances, the immune system can be compromised (decreased lymphoid cellularity, alterations in lymphocyte subpopulations, decreased host resistance, and altered specific immune function responses) in the absence of observed toxicity in other organ systems.

A recent meeting of the British Toxicology Society ('Toxicology and the Immune System', New College Oxford, March) provided an opportunity for some remedial work toward a wider appreciation of the issues which exercise immunotoxicologists, and the ways in which they are being by: 6.

About MyAccess. If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to. Documenting toxic effects upon the immune system is a difficult task due to the multifaceted network of specialized cells that carry out immune functions.

Because of this complexity, it is necessary to develop a panel of immunologic assays to adequately cover the diverse functions that may be affected by a toxic by:   The immune system can be activated by many “non-self” substances.

These are called antigens. The proteins on the surfaces of bacteria, fungi and viruses, for example, are all antigens.

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When the antigens bind to, for example, special receptors on the defense cells, a series of cell processes is started. Then the immune system can recall. Provides a comprehensive basic overview of the science of toxicology, including important concepts from anatomy, physiology, and biochemistry to facilitate the understanding of the principles and mechanisms of toxicant action on specific organ systems.

Presented in full color, each chapter features a summary of key points at the beginning and review questions at the end. In “General Toxicology” the vastness of the toxicological scope is presented by outlining the possible encounter with toxicants of different origins, their fate in the human body and the effects produced.

The book smoothly introduces the reader to the basic principles and mechanisms in the body exposed to ubiquitous foreign substances.

Functional components of the immune response include activities of leukocyte subsets (T lympho­cytes, B lymphocytes, natural killer lymphocytes, mono• .Presents the scientific basis to toxicology as it applies to the workplace and the environment.

The third edition is compact and practical with information structured for easy use by health professionals in both industry and government. The book takes an applied, as opposed to theoretical, scientific approach.

Emphasis is placed on the information pertinent to the industrial environment.